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pentobarbital will minimize the level or effect of buprenorphine, long-performing injection by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Sufferers who transfer to buprenorphine extended-performing injection from transmucosal buprenorphine coadministered with CYP3A4 inducers must be monitored to make cer